Nettie Cullen - Psychologist

"I’m an expert on poisons, Watson.  I know virtually everything there is to know about them.  But I’ve come to learn over the last few years that there is nothing on this planet quite so toxic as guilt."                                                                    Sherlock Holmes, Elementary.

...guilt, but perhaps more so it's close relative shame, can influence our behaviour, our relationships, the way we see the world and the way we perceive ourselves.  Like a poison, it can pervade our whole being.